Tyrosine phosphorylation of Rac1: a role in regulation of cell spreading.

Rac1 influences a multiplicity of vital cellular- and tissue-level control functions, making it an important candidate for targeted therapeutics. The activity of the Rho family member Cdc42 has been shown to be modulated by tyrosine phosphorylation at position 64. We therefore investigated consequen...

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Bibliographic Details
Main Authors: Fumin Chang, Christopher Lemmon, Daniel Lietha, Michael Eck, Lewis Romer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3232246?pdf=render