Clinical and Biochemical Manifestations of Depression: Relation to the Neurobiology of Stress

Major depressive disorder (MDD) is a chronic, recurrent, and severe psychiatric disorder with high mortality and medical comorbidities. Stress-related pathways have been directly involved in the pathophysiology and treatment of MDD. The present paper provides an overview on the stress system as a mo...

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Bibliographic Details
Main Authors: Phillip W. Gold, Rodrigo Machado-Vieira, Maria G. Pavlatou
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2015/581976