Arrest defective-1 controls tumor cell behavior by acetylating myosin light chain kinase.

BACKGROUND:The enhancement of cell motility is a critical event during tumor cell spreading. Since myosin light chain kinase (MLCK) regulates cell behavior, it is regarded as a promising target in terms of preventing tumor invasion and metastasis. Since MLCK was identified to be associated with huma...

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Bibliographic Details
Main Authors: Dong Hoon Shin, Yang-Sook Chun, Kyoung-Hwa Lee, Hyun-Woo Shin, Jong-Wan Park
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2758594?pdf=render