Dnd Is a Critical Specifier of Primordial Germ Cells in the Medaka Fish

Dnd Is a Critical Specifier of Primordial Germ Cells in the Medaka Fish

Primordial germ cell (PGC) specification occurs early in development. PGC specifiers have been identified in Drosophila, mouse, and human but remained elusive in most animals. Here we identify the RNA-binding protein Dnd as a critical PGC specifier in the medaka fish (Oryzias latipes). Dnd depletion...

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Bibliographic Details
Main Authors: Ni Hong, Mingyou Li, Yongming Yuan, Tiansu Wang, Meisheng Yi, Hongyan Xu, Huaqiang Zeng, Jianxing Song, Yunhan Hong
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Stem Cell Reports
Subjects:
asymmetric segregation: dnd
lineage tracing
primordial germ cell
RNA particle
single-cell culture
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671116000199

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http://www.sciencedirect.com/science/article/pii/S2213671116000199

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