Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target.
Schistosomiasis--infection with helminth parasites in the genus Schistosoma, including S. mansoni--is a widespread, devastating tropical disease affecting more than 200 million people. No vaccine is available, and praziquantel, the only drug extensively utilized, is currently administered more than...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-06-01
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Series: | PLoS Medicine |
Online Access: | http://europepmc.org/articles/PMC1892040?pdf=render |