Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target.

Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target.

Schistosomiasis--infection with helminth parasites in the genus Schistosoma, including S. mansoni--is a widespread, devastating tropical disease affecting more than 200 million people. No vaccine is available, and praziquantel, the only drug extensively utilized, is currently administered more than...

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Bibliographic Details
Main Authors: Angela N Kuntz, Elisabeth Davioud-Charvet, Ahmed A Sayed, Lindsay L Califf, Jean Dessolin, Elias S J Arnér, David L Williams
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-06-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC1892040?pdf=render

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http://europepmc.org/articles/PMC1892040?pdf=render

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