Sequence imputation of HPV16 genomes for genetic association studies.

Human Papillomavirus type 16 (HPV16) causes over half of all cervical cancer and some HPV16 variants are more oncogenic than others. The genetic basis for the extraordinary oncogenic properties of HPV16 compared to other HPVs is unknown. In addition, we neither know which nucleotides vary across and...

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Bibliographic Details
Main Authors: Benjamin Smith, Zigui Chen, Laura Reimers, Koenraad van Doorslaer, Mark Schiffman, Rob Desalle, Rolando Herrero, Kai Yu, Sholom Wacholder, Tao Wang, Robert D Burk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3121793?pdf=render