Cell-autonomous regulation of epithelial cell quiescence by calcium channel Trpv6

Epithelial homeostasis and regeneration require a pool of quiescent cells. How the quiescent cells are established and maintained is poorly understood. Here, we report that Trpv6, a cation channel responsible for epithelial Ca2+ absorption, functions as a key regulator of cellular quiescence. Geneti...

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Bibliographic Details
Main Authors: Yi Xin, Allison Malick, Meiqin Hu, Chengdong Liu, Heya Batah, Haoxing Xu, Cunming Duan
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-09-01
Series:eLife
Subjects:
Akt
Tor
Erk
Online Access:https://elifesciences.org/articles/48003