Epigenetic Therapy in Human Choriocarcinoma

Because epigenetic alterations are believed to be involved in the repression of tumor suppressor genes and promotion of tumorigenesis in choriocarcinomas, novel compounds endowed with a histone deacetylase (HDAC) inhibitory activity are an attractive therapeutic approach. HDAC inhibitors (HDACIs) we...

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Bibliographic Details
Main Authors: Hisashi Narahara, Noriyuki Takai
Format: Article
Language:English
Published: MDPI AG 2010-09-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/2/3/1683/