Time- and Race-Specific Haematological Reference Intervals for Healthy Volunteer Trials: A Retrospective Analysis of Pooled Data From Multiple Phase I Trials

Time- and Race-Specific Haematological Reference Intervals for Healthy Volunteer Trials: A Retrospective Analysis of Pooled Data From Multiple Phase I Trials

Most UK hospitals, laboratories, and research institutions use uniform reference intervals (RI) that do not take into account known diurnal and racial variation in total white blood cells (WBC) count and its constituent parameters. These risks of excluding potentially suitable ethnic minority volunt...

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Bibliographic Details
Main Authors: Simon Coates, Duolao Wang, Tomasz Pierscionek, Sara Fernandes, Dilshat Djumanov, Ulrike Lorch, Jörg Täubel
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Pharmacology
Subjects:
white blood cell
racial
diurnal
inclusion criteria
reference intervals
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00314/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00314/full

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