Influenza-induced immune suppression to methicillin-resistant Staphylococcus aureus is mediated by TLR9.

Influenza-induced immune suppression to methicillin-resistant Staphylococcus aureus is mediated by TLR9.

Bacterial lung infections, particularly with methicillin-resistant Staphylococcus aureus (MRSA), increase mortality following influenza infection, but the mechanisms remain unclear. Here we show that expression of TLR9, a microbial DNA sensor, is increased in murine lung macrophages, dendritic cells...

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Bibliographic Details
Main Authors: Giovanny J Martínez-Colón, Helen Warheit-Niemi, Stephen J Gurczynski, Quincy M Taylor, Carol A Wilke, Amy B Podsiad, Joel Crespo, Urvashi Bhan, Bethany B Moore
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007560

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https://doi.org/10.1371/journal.ppat.1007560

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