Dermal-type macrophages expressing CD209/DC-SIGN show inherent resistance to dengue virus growth.

Dermal-type macrophages expressing CD209/DC-SIGN show inherent resistance to dengue virus growth.

BACKGROUND: An important question in dengue pathogenesis is the identity of immune cells involved in the control of dengue virus infection at the site of the mosquito bite. There is evidence that infection of immature myeloid dendritic cells plays a crucial role in dengue pathogenesis and that the i...

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Main Authors: Wing-Hong Kwan, Erika Navarro-Sanchez, Hélène Dumortier, Marion Decossas, Hortense Vachon, Flavia Barreto dos Santos, Hervé W Fridman, Félix A Rey, Eva Harris, Philippe Despres, Christopher G Mueller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2553280?pdf=render

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http://europepmc.org/articles/PMC2553280?pdf=render

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