Intracochlear PLGA based implants for dexamethasone release: Challenges and solutions

The effective treatment of diseases of the inner ear is currently an unmet medical need. Local controlled drug delivery to the cochlea is challenging due to the hidden location, small volume and high sensitivity of this organ. A local intracochlear delivery of drugs would avoid the problems of intra...

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Bibliographic Details
Main Authors: E. Lehner, D. Gündel, A. Liebau, S. Plontke, K. Mäder
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:International Journal of Pharmaceutics: X
Online Access:http://www.sciencedirect.com/science/article/pii/S2590156719300295