A Primate Model of Huntington'S Disease: Functional Neural Transplantation and Ct-Guided Stereotactic Procedures

In this article, we show that 1) computed tomographic (CT)-guided stereotactic infusion of an excitotoxin into the striatum of a nonhuman primate provides a useful neuropathologic and behavioral model for Huntington's disease. 2) High-resolution positron emission tomography (PET) can be used to...

Full description

Bibliographic Details
Main Authors: James M. Schumacher, Philippe Hantraye, Anna-Lisa Brownell, Danielle Riche, Bertha K. Madras, Paula D. Davenport, Mariannick Maziere, David R. Elmaleh, Gordon L. Brownell, Ole Isacson
Format: Article
Language:English
Published: SAGE Publishing 1992-07-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/096368979200100409