Disruption of the RNA modifications that target the ribosome translation machinery in human cancer

Disruption of the RNA modifications that target the ribosome translation machinery in human cancer

Abstract Genetic and epigenetic changes deregulate RNA and protein expression in cancer cells. In this regard, tumors exhibit an abnormal proteome in comparison to the corresponding normal tissues. Translation control is a crucial step in the regulation of gene expression regulation under normal and...

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Bibliographic Details
Main Authors: Maxime Janin, Laia Coll-SanMartin, Manel Esteller
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Molecular Cancer
Subjects:
Ribosomal RNA
Transfer RNA
Translation
Human cancer
Epitranscriptomics
Online Access:http://link.springer.com/article/10.1186/s12943-020-01192-8

Internet

http://link.springer.com/article/10.1186/s12943-020-01192-8

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