The Plasmodium falciparum Rh5 invasion protein complex reveals an excess of rare variant mutations

Abstract Background The invasion of the red blood cells by Plasmodium falciparum merozoites involves the interplay of several proteins that are also targets for vaccine development. The proteins PfRh5-PfRipr-PfCyRPA-Pfp113 assemble into a complex at the apical end of the merozoite and are together e...

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Bibliographic Details
Main Authors: Leonard Ndwiga, Victor Osoti, Kevin Omondi Ochwedo, Kevin Wamae, Philip Bejon, Julian C. Rayner, George Githinji, Lynette Isabella Ochola-Oyier
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Malaria Journal
Subjects:
Rh5
Online Access:https://doi.org/10.1186/s12936-021-03815-x