Cytoplasmic glycoengineering of Apx toxin fragments in the development of Actinobacillus pleuropneumoniae glycoconjugate vaccines

Abstract Background Actinobacillus pleuropneumoniae is the causative agent of porcine pleuropneumonia and represents a major burden to the livestock industry. Virulence can largely be attributed to the secretion of a series of haemolytic toxins, which are highly immunogenic. A. pleuropneumoniae also...

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Bibliographic Details
Main Authors: Ian J. Passmore, Anna Andrejeva, Brendan W. Wren, Jon Cuccui
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Veterinary Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12917-018-1751-2