Growth Suppression in Lung Cancer Cells Harboring EGFR-C797S Mutation by Quercetin

Growth Suppression in Lung Cancer Cells Harboring EGFR-C797S Mutation by Quercetin

Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are approved treatments for non-small-cell lung cancer (NSCLC) patients harboring activating EGFR mutations. The EGFR C797S mutation is one of the known acquired-resistance mutations to the latest third-generation TKIs. At pre...

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Bibliographic Details
Main Authors: Kuo-Yen Huang, Tong-Hong Wang, Chin-Chuan Chen, Yann-Lii Leu, Hsin-Jung Li, Cai-Ling Jhong, Chi-Yuan Chen
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Biomolecules
Subjects:
AXL
EGFR C797S
lung cancer
quercetin
TKI resistance
Online Access:https://www.mdpi.com/2218-273X/11/9/1271

Internet

https://www.mdpi.com/2218-273X/11/9/1271

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