Antibacterial Activity and Membrane-Disruptive Mechanism of 3-p-trans-Coumaroyl-2-hydroxyquinic Acid, a Novel Phenolic Compound from Pine Needles of Cedrus deodara, against Staphylococcus aureus

Antibacterial Activity and Membrane-Disruptive Mechanism of 3-p-trans-Coumaroyl-2-hydroxyquinic Acid, a Novel Phenolic Compound from Pine Needles of Cedrus deodara, against Staphylococcus aureus

Recently, we reported that a novel phenolic compound isolated from Cedrus deodara, 3-p-trans-coumaroyl-2-hydroxyquinic acid (CHQA), exhibits a potent antioxidant activity. The present study aimed to evaluate the antibacterial activity of CHQA against eleven food-borne pathogens and to elucidate its...

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Bibliographic Details
Main Authors: Yanping Wu, Jinrong Bai, Kai Zhong, Yina Huang, Huayi Qi, Yan Jiang, Hong Gao
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:Molecules
Subjects:
phenolic compound
Staphylococcus aureus
antibacterial activity
antibacterial mechanism
membrane damage
Online Access:http://www.mdpi.com/1420-3049/21/8/1084

Internet

http://www.mdpi.com/1420-3049/21/8/1084

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