An Integrative Transcriptomic and Metabolomic Study Revealed That Melatonin Plays a Protective Role in Chronic Lung Inflammation by Reducing Necroptosis

An Integrative Transcriptomic and Metabolomic Study Revealed That Melatonin Plays a Protective Role in Chronic Lung Inflammation by Reducing Necroptosis

It has been reported that melatonin can relieve the symptoms of chronic obstructive pulmonary disease (COPD) by improving sleep quality, that is to say, the pineal secreted hormone melatonin has a protective effect in the pathogenesis of COPD, but its underlying mechanism remains unclear. In this st...

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Bibliographic Details
Main Authors: Kaimin Mao, Ping Luo, Wei Geng, Juanjuan Xu, Yuhan Liao, Hua Zhong, Pei Ma, Qi Tan, Hui Xia, Limin Duan, Siwei Song, Danling Long, Yuqi Liu, Tinglin Yang, Yali Wu, Yang Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
melatonin
COPD
chronic lung inflammation
transcriptomic
metabolomic
necroptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.668002/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.668002/full

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