Impact of Ozone, Sex, and Gonadal Hormones on Bronchoalveolar Lavage Characteristics and Survival in SP-A KO Mice Infected with <i>Klebsiella pneumoniae</i>

Impact of Ozone, Sex, and Gonadal Hormones on Bronchoalveolar Lavage Characteristics and Survival in SP-A KO Mice Infected with <i>Klebsiella pneumoniae</i>

Surfactant protein A (SP-A) plays an important role in innate immunity. The sex-dependent survival of infected SP-A knockout (KO) mice has been observed. Our goal was to study the impact of ozone (O<sub>3</sub>) and sex, as well as gonadal hormones, on the bronchoalveolar lavage (BAL) re...

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Bibliographic Details
Main Authors: Chintan K. Gandhi, Anatoly N. Mikerov, Faryal Durrani, Todd M. Umstead, Sanmei Hu, Guirong Wang, David S. Phelps, Joanna Floros
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Microorganisms
Subjects:
sex differences
oxidative stress
surfactant protein-A
pneumonia
innate immunity
Online Access:https://www.mdpi.com/2076-2607/8/9/1354

Internet

https://www.mdpi.com/2076-2607/8/9/1354

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