Histone Deacetylase 11 Contributes to Renal Fibrosis by Repressing KLF15 Transcription

Renal fibrosis represents a key pathophysiological process in patients with chronic kidney diseases (CKD) and is typically associated with a poor prognosis. Renal tubular epithelial cells (RTECs), in response to a host of pro-fibrogenic stimuli, can trans-differentiate into myofibroblast-like cells...

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Bibliographic Details
Main Authors: Lei Mao, Li Liu, Tao Zhang, Hao Qin, Xiaoyan Wu, Yong Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00235/full