Effects of shikonin on the development of ovarian follicles and female germline stem cells

Objective To investigate the effects and potential mechanism of action of shikonin (SHK) on the development of ovarian follicles and female germline stem cells (FGSCs). Methods Female Kunming adult mice were administered SHK (0, 20 and 50 mg/kg) by oral gavage. Cultures of FGSCs were treated with SH...

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Bibliographic Details
Main Authors: Shu-Xin Ma, Li-Bo Tang, Zhi-Hang Chen, Min-Li Wei, Zi-Juan Tang, Yue-Hui Zheng, Guo Zong, Jia Li
Format: Article
Language:English
Published: SAGE Publishing 2021-07-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/03000605211029461