WDR5, BRCA1, and BARD1 Co-regulate the DNA Damage Response and Modulate the Mesenchymal-to-Epithelial Transition during Early Reprogramming

WDR5, BRCA1, and BARD1 Co-regulate the DNA Damage Response and Modulate the Mesenchymal-to-Epithelial Transition during Early Reprogramming

Summary: Differentiated cells are epigenetically stable, but can be reprogrammed to pluripotency by expression of the OSKM transcription factors. Despite significant effort, relatively little is known about the cellular requirements for reprogramming and how they affect the properties of induced plu...

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Main Authors: Georgina Peñalosa-Ruiz, Vicky Bousgouni, Jan P. Gerlach, Susan Waarlo, Joris V. van de Ven, Tim E. Veenstra, José C.R. Silva, Simon J. van Heeringen, Chris Bakal, Klaas W. Mulder, Gert Jan C. Veenstra
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671119300542

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http://www.sciencedirect.com/science/article/pii/S2213671119300542

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