Lysosomal Enzyme Glucocerebrosidase Protects against Aβ1-42 Oligomer-Induced Neurotoxicity.

Lysosomal Enzyme Glucocerebrosidase Protects against Aβ1-42 Oligomer-Induced Neurotoxicity.

Glucocerebrosidase (GCase) functions as a lysosomal enzyme and its mutations are known to be related to many neurodegenerative diseases, including Gaucher's disease (GD), Parkinson's disease (PD), and Dementia with Lewy Bodies (DLB). However, there is little information about the role of G...

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Bibliographic Details
Main Authors: Seulah Choi, Donghoon Kim, Tae-In Kam, Seungpil Yun, Sangjune Kim, Hyejin Park, Heehong Hwang, Olga Pletnikova, Juan C Troncoso, Valina L Dawson, Ted M Dawson, Han Seok Ko
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4668030?pdf=render

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http://europepmc.org/articles/PMC4668030?pdf=render

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