Methylation Analysis in Monozygotic Twins With Treatment-Resistant Schizophrenia and Discordant Responses to Clozapine

Methylation Analysis in Monozygotic Twins With Treatment-Resistant Schizophrenia and Discordant Responses to Clozapine

Schizophrenia is a mental illness that involves both genetic and environmental factors. Clozapine, an atypical antipsychotic, is a well-established therapy for treatment-resistant schizophrenia. In this study, we focused on a set of monozygotic twins with treatment-resistant schizophrenia in which o...

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Bibliographic Details
Main Authors: Masataka Kikuchi, Takanobu Nakazawa, Makoto Kinoshita, Hidenaga Yamamori, Yuka Yasuda, Michiko Fujimoto, Ryota Hashimoto, Shusuke Numata
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Psychiatry
Subjects:
schizophrenia
clozapine
DNA methylation
monozygotic twins
iPS cells
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2021.734606/full

Internet

https://www.frontiersin.org/articles/10.3389/fpsyt.2021.734606/full

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