The Effect of Docetaxel (Taxotere®) on Human Gastric Cancer Cells Exhibiting Low-Dose Radiation Hypersensitivity

Low-dose radiation hypersensitivity (HRS) describes a phenomenon of excessive sensitivity to X ray doses <0.5 Gy. Docetaxel is a taxane shown to arrest cells in the G 2 /M phase of the cell cycle. Some previous studies suggested that HRS might result from the abrogation of the early G 2 checkpoin...

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Bibliographic Details
Main Authors: Elizabeth K. Balcer-Kubiczek Ph.D., Mona Attarpour, Jian Z. Wang, William F. Regine
Format: Article
Language:English
Published: SAGE Publishing 2008-01-01
Series:Clinical Medicine Insights: Oncology
Online Access:https://doi.org/10.4137/CMO.S463