The hypoxic microenvironment: a driving force for heterotopic ossification progression

Abstract Heterotopic ossification (HO) refers to the formation of bone tissue outside the normal skeletal system. According to its pathogenesis, HO is divided into hereditary HO and acquired HO. There currently lack effective approaches for HO prevention or treatment. A deep understanding of its pat...

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Bibliographic Details
Main Authors: Yifei Huang, Xinyi Wang, Hui Lin
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Cell Communication and Signaling
Subjects:
Online Access:https://doi.org/10.1186/s12964-020-0509-1