High fat diet induced developmental defects in the mouse: oocyte meiotic aneuploidy and fetal growth retardation/brain defects.

High fat diet induced developmental defects in the mouse: oocyte meiotic aneuploidy and fetal growth retardation/brain defects.

Maternal obesity is associated with poor outcomes across the reproductive spectrum including infertility, increased time to pregnancy, early pregnancy loss, fetal loss, congenital abnormalities and neonatal conditions. Furthermore, the proportion of reproductive-aged woman that are obese in the popu...

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Bibliographic Details
Main Authors: Kerri M Luzzo, Qiang Wang, Scott H Purcell, Maggie Chi, Patricia T Jimenez, Natalia Grindler, Tim Schedl, Kelle H Moley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3495769?pdf=render

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http://europepmc.org/articles/PMC3495769?pdf=render

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