Single-molecule quantification of 5-hydroxymethylcytosine for diagnosis of blood and colon cancers

Abstract Background The DNA modification 5-hydroxymethylcytosine (5hmC) is now referred to as the sixth base of DNA with evidence of tissue-specific patterns and correlation with gene regulation and expression. This epigenetic mark was recently reported as a potential biomarker for multiple types of...

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Bibliographic Details
Main Authors: Noa Gilat, Tzlil Tabachnik, Amit Shwartz, Tamar Shahal, Dmitry Torchinsky, Yael Michaeli, Gil Nifker, Shahar Zirkin, Yuval Ebenstein
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Clinical Epigenetics
Subjects:
CRC
Online Access:http://link.springer.com/article/10.1186/s13148-017-0368-9