Modulating autophagy in mesenchymal stem cells effectively protects against hypoxia- or ischemia-induced injury

Abstract In mammals, a basal level of autophagy, a self-eating cellular process, degrades cytosolic proteins and subcellular organelles in lysosomes to provide energy, recycles the cytoplasmic components, and regenerates cellular building blocks; thus, autophagy maintains cellular and tissue homeost...

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Bibliographic Details
Main Authors: Chenxia Hu, Lingfei Zhao, Daxian Wu, Lanjuan Li
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Stem Cell Research & Therapy
Online Access:http://link.springer.com/article/10.1186/s13287-019-1225-x