MC4R Variant rs17782313 Associates With Increased Levels of DNAJC27, Ghrelin, and Visfatin and Correlates With Obesity and Hypertension in a Kuwaiti Cohort

MC4R Variant rs17782313 Associates With Increased Levels of DNAJC27, Ghrelin, and Visfatin and Correlates With Obesity and Hypertension in a Kuwaiti Cohort

Melanocortin 4 receptor (MC4R), a notable component of the melanocortin system, regulates appetite, body weight, and energy homeostasis. Genome-wide association studies have identified several MC4R variants associated with adiposity; of these, rs17782313, which is associated with increased body mass...

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Bibliographic Details
Main Authors: Maha M. Hammad, Mohamed Abu-Farha, Prashantha Hebbar, Preethi Cherian, Irina Al Khairi, Motasem Melhem, Fadi Alkayal, Osama Alsmadi, Thangavel Alphonse Thanaraj, Fahd Al-Mulla, Jehad Abubaker
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Endocrinology
Subjects:
cAMP
DNAJC27
ghrelin
MC4R
obesity
visfatin
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00437/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2020.00437/full

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