A Simple Sperm DNA Toroid Integrity Test and Risk of Miscarriage

Current methods of analyzing sperm chromatin competency overlook the inner sperm compartment which is inaccessible to probes and reagents. By breaking the molecular protamine disulfide bridges, the DNA toroids are exposed to integrity analysis. The aim was to develop a simple nuclear toroid test and...

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Bibliographic Details
Main Authors: Philip J. Chan, Eliza M. Orzylowska, Johannah U. Corselli, John D. Jacobson, Albert K. Wei
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/780983