Inhibition of Delta-like Ligand 4 enhances the radiosensitivity and inhibits migration in cervical cancer via the reversion of epithelial–mesenchymal transition

Inhibition of Delta-like Ligand 4 enhances the radiosensitivity and inhibits migration in cervical cancer via the reversion of epithelial–mesenchymal transition

Abstract Background Concurrent chemoradiotherapy is the common first-line treatment for patients with advanced cervical cancer. However, radioresistance remains a major clinical challenge, which results in recurrence and poor survival. Many studies have shown the potential of Delta-like Ligand 4 (DL...

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Bibliographic Details
Main Authors: Shan-Shan Yang, De-Yang Yu, Yu-Ting Du, Le Wang, Lina Gu, Yun-Yan Zhang, Min Xiao
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Cancer Cell International
Subjects:
DLL4
Cervical cancer
Radiosensitivity
Progression
Epithelial–mesenchymal transition
Online Access:http://link.springer.com/article/10.1186/s12935-020-01434-1

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http://link.springer.com/article/10.1186/s12935-020-01434-1

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