Aryl hydrocarbon receptor activation mediates kidney disease and renal cell carcinoma

Abstract The aryl hydrocarbon receptor (AhR) is a well-known ligand-activated cytoplasmic transcription factor that contributes to cellular responses against environmental toxins and carcinogens. AhR is activated by a range of structurally diverse compounds from the environment, microbiome, natural...

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Bibliographic Details
Main Authors: Hui Zhao, Lin Chen, Tian Yang, Ya-Long Feng, Nosratola D. Vaziri, Bao-Li Liu, Qing-Quan Liu, Yan Guo, Ying-Yong Zhao
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Journal of Translational Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12967-019-2054-5