Down-regulation of E-cadherin enhances prostate cancer chemoresistance via Notch signaling
Abstract Background The chemoresistance of prostate cancer (PCa) is invariably associated with the aggressiveness and metastasis of this disease. New emerging evidence indicates that the epithelial-to-mesenchymal transition (EMT) may play pivotal roles in the development of chemoresistance and metas...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-03-01
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Series: | Chinese Journal of Cancer |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s40880-017-0203-x |