Testing for heterogeneity among the components of a binary composite outcome in a clinical trial

<p>Abstract</p> <p>Background</p> <p>Investigators designing clinical trials often use composite outcomes to overcome many statistical issues. Trialists want to maximize power to show a statistically significant treatment effect and avoid inflation of Type I error rate...

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Bibliographic Details
Main Authors: Devereaux PJ, Thabane Lehana, Pogue Janice, Yusuf Salim
Format: Article
Language:English
Published: BMC 2010-06-01
Series:BMC Medical Research Methodology
Online Access:http://www.biomedcentral.com/1471-2288/10/49