Optogenetic long-term manipulation of behavior and animal development.

Channelrhodopsin-2 (ChR2) is widely used for rapid photodepolarization of neurons, yet, as it requires high-intensity blue light for activation, it is not suited for long-term in vivo applications, e.g. for manipulations of behavior, or photoactivation of neurons during development. We used "sl...

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Bibliographic Details
Main Authors: Christian Schultheis, Jana Fiona Liewald, Ernst Bamberg, Georg Nagel, Alexander Gottschalk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3080377?pdf=render