Analysis of mice lacking DNaseI hypersensitive sites at the 5' end of the IgH locus.

The 5' end of the IgH locus contains a cluster of DNaseI hypersensitive sites, one of which (HS1) was shown to be pro-B cell specific and to contain binding sites for the transcription factors PU.1, E2A, and Pax5. These data as well as the location of the hypersensitive sites at the 5' bor...

Full description

Bibliographic Details
Main Authors: Thomas Perlot, Inka Pawlitzky, John P Manis, Ali A Zarrin, Peter H Brodeur, Frederick W Alt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2981565?pdf=render