Long Noncoding RNA LINC-PINT Suppresses Cell Proliferation, Invasion, and EMT by Blocking Wnt/β-Catenin Signaling in Glioblastoma

Long Noncoding RNA LINC-PINT Suppresses Cell Proliferation, Invasion, and EMT by Blocking Wnt/β-Catenin Signaling in Glioblastoma

Background: Glioblastoma (GBM) represents the most aggressive glioma with high invasive potential. Recent studies proved the involvement of epithelial-mesenchymal transition (EMT) process in increasing the malignancy and invasiveness of GBM. LncRNAs have been verified to play pivotal roles in human...

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Bibliographic Details
Main Authors: Hanshuo Zhu, Zheng Chen, Lin Shen, Tianchi Tang, Min Yang, Xuesheng Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Pharmacology
Subjects:
glioblastoma
LINC-PINT
epithelial-mesenchymal transition
Wnt/β-catenin signaling
lncRNAs
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.586653/full

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https://www.frontiersin.org/articles/10.3389/fphar.2020.586653/full

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