Susceptibility of aging mice to listeriosis: Role of anti-inflammatory responses with enhanced Treg-cell expression of CD39/CD73 and Th-17 cells

Foodborne Listeria monocytogenes (Lm) causes serious illness and death in immunosuppressed hosts, including the elderly population. We investigated Lm susceptibility and inflammatory cytokines in geriatric mice. Young-adult and old mice were gavaged with a Lm strain Lmo-InlAm. Tissues were assayed f...

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Bibliographic Details
Main Authors: M. Samiul Alam, Christopher Cavanaugh, Marion Pereira, Uma Babu, Kristina Williams
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:International Journal of Medical Microbiology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1438422120300072