Reverse Signaling Contributes to Control of Chronic Inflammation by Anti-TNF Therapeutics

Reverse Signaling Contributes to Control of Chronic Inflammation by Anti-TNF Therapeutics

Anti-tumor necrosis factor (TNF) monoclonal antibodies and TNF receptor ectodomain fusion protein are in clinical use to neutralize circulating TNF and ameliorate symptoms of many autoimmune diseases and pathological conditions with chronic inflammation. In this paper we present data to prove that r...

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Bibliographic Details
Main Authors: Orsolya Sipos, Annamária Török, Tanja Kalic, Ernő Duda, Kata Filkor
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:Antibodies
Subjects:
autoimmune
monoclonal antibodies
inflammation
macrophage
reverse signal
tumor necrosis factor (TNF)
TNF receptor
Online Access:http://www.mdpi.com/2073-4468/4/2/123

Internet

http://www.mdpi.com/2073-4468/4/2/123

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