Nucleosomes influence multiple steps during replication initiation

Nucleosomes influence multiple steps during replication initiation

Eukaryotic replication origin licensing, activation and timing are influenced by chromatin but a mechanistic understanding is lacking. Using reconstituted nucleosomal DNA replication assays, we assessed the impact of nucleosomes on replication initiation. To generate distinct nucleosomal landscapes,...

Full description

Bibliographic Details
Main Authors: Ishara F Azmi, Shinya Watanabe, Michael F Maloney, Sukhyun Kang, Jason A Belsky, David M MacAlpine, Craig L Peterson, Stephen P Bell
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-03-01
Series:eLife
Subjects:
DNA Replication
Helicase
Eukaryotic
nucleosome
chromatin remodeling enzyme
origin licensing
Online Access:https://elifesciences.org/articles/22512

Internet

https://elifesciences.org/articles/22512

Similar Items