Detection and quantification of SARS-CoV-2 by droplet digital PCR in real-time PCR negative nasopharyngeal swabs from suspected COVID-19 patients.

Detection and quantification of SARS-CoV-2 by droplet digital PCR in real-time PCR negative nasopharyngeal swabs from suspected COVID-19 patients.

Show other versions (1)

Since SARS-CoV-2-based disease (COVID-19) spreads as a pandemic, the necessity of a highly sensitive molecular diagnosis that can drastically reduce false negatives reverse transcription PCR (rtPCR) results, raises as a major clinical need. Here we evaluated the performance of a ddPCR-based assay to...

Full description

Bibliographic Details
Main Authors: Claudia Alteri, Valeria Cento, Maria Antonello, Luna Colagrossi, Marco Merli, Nicola Ughi, Silvia Renica, Elisa Matarazzo, Federica Di Ruscio, Livia Tartaglione, Jacopo Colombo, Chiara Grimaldi, Stefania Carta, Alice Nava, Valentino Costabile, Chiara Baiguera, Daniela Campisi, Diana Fanti, Chiara Vismara, Roberto Fumagalli, Francesco Scaglione, Oscar Massimiliano Epis, Massimo Puoti, Carlo Federico Perno
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0236311

Internet

https://doi.org/10.1371/journal.pone.0236311

Similar Items