Transcriptomics in type 2 diabetes: Bridging the gap between genotype and phenotype

Transcriptomics in type 2 diabetes: Bridging the gap between genotype and phenotype

Type 2 diabetes (T2D) is a common, multifactorial disease that is influenced by genetic and environmental factors and their interactions. However, common variants identified by genome wide association studies (GWAS) explain only about 10% of the total trait variance for T2D and less than 5% of the v...

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Bibliographic Details
Main Authors: Christopher P. Jenkinson, Harald H.H. Göring, Rector Arya, John Blangero, Ravindranath Duggirala, Ralph A. DeFronzo
Format: Article
Language:English
Published: Elsevier 2016-06-01
Series:Genomics Data
Subjects:
Type 2 diabetes
Insulin resistance
Obesity
Gene expression
Mexican Americans
VAGES
ADH1B
Transcriptomics
GWAS
eQTL
Online Access:http://www.sciencedirect.com/science/article/pii/S2213596015301021

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http://www.sciencedirect.com/science/article/pii/S2213596015301021

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