Actionable gene expression-based patient stratification for molecular targeted therapy in hepatocellular carcinoma.

Actionable gene expression-based patient stratification for molecular targeted therapy in hepatocellular carcinoma.

BACKGROUND: The effectiveness of molecular targeted agents is modest in hepatocellular carcinoma (HCC). Efficacy of molecular targeted therapies has been better in cancer patients with high expression of actionable molecules defined as cognate target molecules. However, patient stratification based...

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Main Authors: Jung-Hee Kwon, Namgyu Lee, Jin Young Park, Yun Suk Yu, Jin Pyo Kim, Ji Hye Shin, Dong-Sik Kim, Jae Won Joh, Dae Shick Kim, Kwan Yong Choi, Koo-Jeong Kang, Gundo Kim, Young Ho Moon, Hee Jung Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3681850?pdf=render

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http://europepmc.org/articles/PMC3681850?pdf=render

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