First-line treatment for chronic myeloid leukemia: dasatinib, nilotinib, or imatinib

<p>Abstract</p> <p>Imatinib, a tyrosine kinase inhibitor (TKI) of BCR-ABL, was the standard first-line therapy for chronic myeloid leukemia (CML) for almost 10 years. Dasatinib and nilotinib, two newer drugs with higher potency than imatinib against BCR-ABL and activity against mos...

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Bibliographic Details
Main Authors: Rafiyath Shamudheen, Wei Guoqing, Liu Delong
Format: Article
Language:English
Published: BMC 2010-11-01
Series:Journal of Hematology & Oncology
Online Access:http://www.jhoonline.org/content/3/1/47