Serial femtosecond X-ray diffraction of enveloped virus microcrystals

Serial femtosecond X-ray diffraction of enveloped virus microcrystals

Serial femtosecond crystallography (SFX) using X-ray free-electron lasers has produced high-resolution, room temperature, time-resolved protein structures. We report preliminary SFX of Sindbis virus, an enveloped icosahedral RNA virus with ∼700 Å diameter. Microcrystals delivered in viscous agarose...

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Bibliographic Details
Main Authors: Robert M. Lawrence, Chelsie E. Conrad, Nadia A. Zatsepin, Thomas D. Grant, Haiguang Liu, Daniel James, Garrett Nelson, Ganesh Subramanian, Andrew Aquila, Mark S. Hunter, Mengning Liang, Sébastien Boutet, Jesse Coe, John C. H. Spence, Uwe Weierstall, Wei Liu, Petra Fromme, Vadim Cherezov, Brenda G. Hogue
Format: Article
Language:English
Published: AIP Publishing LLC and ACA 2015-07-01
Series:Structural Dynamics
Online Access:http://dx.doi.org/10.1063/1.4929410

Internet

http://dx.doi.org/10.1063/1.4929410

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