Interleukin-33 Receptor (ST2) Deficiency Improves the Outcome of Staphylococcus aureus-Induced Septic Arthritis

Interleukin-33 Receptor (ST2) Deficiency Improves the Outcome of Staphylococcus aureus-Induced Septic Arthritis

The ST2 receptor is a member of the Toll/IL-1R superfamily and interleukin-33 (IL-33) is its agonist. Recently, it has been demonstrated that IL-33/ST2 axis plays key roles in inflammation and immune mediated diseases. Here, we investigated the effect of ST2 deficiency in Staphylococcus aureus-induc...

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Bibliographic Details
Main Authors: Larissa Staurengo-Ferrari, Silvia C. Trevelin, Victor Fattori, Daniele C. Nascimento, Kalil A. de Lima, Jacinta S. Pelayo, Florêncio Figueiredo, Rubia Casagrande, Sandra Y. Fukada, Mauro M. Teixeira, Thiago M. Cunha, Foo Y. Liew, Rene D. Oliveira, Paulo Louzada-Junior, Fernando Q. Cunha, José C. Alves-Filho, Waldiceu A. Verri
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
Subjects:
interleukin-33
ST2
septic arthritis
Staphylococcus aureus
interferon-γ
nitric oxide
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00962/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00962/full

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