Dynamic behaviors of α-synuclein and tau in the cellular context: New mechanistic insights and therapeutic opportunities in neurodegeneration

α-Synuclein (αS) and tau have a lot in common. Dyshomeostasis and aggregation of both proteins are central in the pathogenesis of neurodegenerative diseases: Parkinson's disease, dementia with Lewy bodies, multi-system atrophy and other ‘synucleinopathies’ in the case of αS; Alzheimer's di...

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Bibliographic Details
Main Authors: Fred Yeboah, Tae-Eun Kim, Anke Bill, Ulf Dettmer
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996119302116