HLA-DRB1 GENE POLYMORPHISMS IN PEDIATRIC PATIENTS WITH TYPE 1 AUTOIMMUNE HEPATITIS AND TYPE 1 AUTOIMMUNE HEPATITIS OVERLAP SYNDROME WITH AUTOIMMUNE CHOLANGITIS

HLA-DRB1 GENE POLYMORPHISMS IN PEDIATRIC PATIENTS WITH TYPE 1 AUTOIMMUNE HEPATITIS AND TYPE 1 AUTOIMMUNE HEPATITIS OVERLAP SYNDROME WITH AUTOIMMUNE CHOLANGITIS

ABSTRACT BACKGROUND: Autoimmune hepatitis (AIH) is a rare chronic inflammatory liver disease associated with a loss of immunological tolerance to self-antigens. Susceptibility to AIH is partially determined by the presence of genes related to human leukocyte antigen (HLA), mainly allelic variants...

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Bibliographic Details
Main Authors: Monique Ellen Gervásio NUNES, Daniela Valadão ROSA, Eleonora Druve Tavares FAGUNDES, Alexandre Rodrigues FERREIRA, Débora Marques de MIRANDA, Priscila Menezes FERRI LIU
Format: Article
Language:English
Published: Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia (IBEPEGE)
Series:Arquivos de Gastroenterologia
Subjects:
Hepatite autoimune
Colangite esclerosante
Cadeias HLA-DRB1
Polimorfismo genético
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032019000200146&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032019000200146&lng=en&tlng=en

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